Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988219 | 1.00 | TBXA2R (0.47) | TBXA2RPPM1BPTPN1PPP1CC | |
| SCHEMBL8870983 | 1.00 | TBXA2R (0.47) | TBXA2RPPM1BPTPN1PPP1CC | |
| SCHEMBL9201397 | 0.87 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL10437533 | 0.87 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL250155 | 0.86 | LMNA (0.41) | TBXA2RPPM1BPTPN1PPP1CC | |
| SCHEMBL9197017 | 0.77 | TBXA2R (0.53) | TBXA2R | |
| SCHEMBL9718067 | 0.77 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL14415445 | 0.76 | SLC6A3 (0.35) | TBXA2R | |
| SCHEMBL9718198 | 0.75 | TBXA2R (0.45) | TBXA2R | |
| SCHEMBL9718203 | 0.75 | TBXA2R (0.45) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618946-A | 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| US-5539130-A | CHEMICAL CONDENSATION FOLLOWED BY CATALYTIC HYDROGENATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5539126-A | PROSTAGLANDIN ANALOGS, THROMBOXANE A2 RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5508445-A | FORMING A CHEMICAL INTERMEDIATE ALDEHYDE, STARTING AN AMINE AND AN ANHYDRIDE TO FORM AN IMIDE, THEN GRIGNARD REACTION, REACTING WITH A REDUCING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0678507-A1 | Method for preparing homochiral maleimide intermediates, via silylation techniques, used in the enantioselective preparation of anti-thrombotic and anti-vasospastic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-25 | — | — | EP | disclosed |
| US-5436347-A | Benzaldehyde intermediates useful in the preparation of 7-oxabicycloheptane carboxylic acid prostaglandin analog anti-thrombotic and anti-vasospastic compounds and method for preparing same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5399725-A | Forming alcohol-amides by reacting a 7-oxabicycloheptane imide with a 2-/2-metallated phenyl/-1,3-dioxolane /metal is lithium or magnesium bromide/ and reducing the product | BRISTOL-MYERS SQUIBB CO. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0626384-A1 | 7-Oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of antithrombotic and anti-vasospastic compounds and method for preparing same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5332840-A | Acylation an anhydride and reaction with oxazolidine to form benzaldehyde | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-07-26 | — | — | US | disclosed |