Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192195 | 0.91 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9197625 | 0.86 | — | — | |
| SCHEMBL7014033 | 0.86 | AGTR2 (0.72) | AGTR1AGTR2 | |
| SCHEMBL7011288 | 0.85 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7017061 | 0.85 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9196961 | 0.85 | — | — | |
| SCHEMBL9085616 | 0.83 | AGTR2 (0.56) | AGTR1AGTR2 | |
| SCHEMBL12829245 | 0.83 | AGTR2 (0.60) | AGTR1AGTR2 | |
| SCHEMBL7145725 | 0.83 | AGTR2 (0.57) | AGTR1AGTR2 | |
| SCHEMBL7016557 | 0.83 | PPARG (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5250554-A | Cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |