Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196021 | 0.92 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ANPC1LMNA | |
| SCHEMBL7288790 | 0.89 | MAPT (0.40) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7291466 | 0.87 | KMT2A (0.37) | ALDH1A1MAPTKMT2ANPC1LMNA | |
| SCHEMBL9195585 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ANPC1LMNA | |
| SCHEMBL7289652 | 0.85 | KMT2A (0.37) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL9411248 | 0.83 | MAPT (0.37) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL7295938 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL8400074 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL8396215 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL9411135 | 0.83 | KMT2A (0.34) | ALDH1A1MAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |