Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019766 | 0.81 | TSHR (0.36) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9575377 | 0.80 | — | — | |
| SCHEMBL9193268 | 0.79 | TSHR (0.34) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL11258229 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9826886 | 0.78 | TDP1 (0.36) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9192156 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL20438400 | 0.76 | — | — | |
| SCHEMBL19543422 | 0.76 | — | — | |
| SCHEMBL5959322 | 0.76 | — | — | |
| SCHEMBL9197104 | 0.75 | MEN1 (0.32) | MEN1KMT2AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448006-B1 | Process for the preparation of acylales | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5231221-A | PROCESS FOR THE PREPARATION OF ACYLALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0448006-A2 | Process for the preparation of acylales | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |