Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | RORA | P35398 | 3/20 | 0.58 |
| ▸ | RORC | P51449 | 3/20 | 0.58 |
| ▸ | RORB | Q92753 | 3/20 | 0.58 |
| ▸ | PDE4A | P27815 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9205421 | 0.99 | PGR (0.57) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9199179 | 0.96 | PGR (0.59) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9204573 | 0.94 | PGR (0.57) | PGRRORARORCRORBPDE4A | |
| Hydrochloric Acid SCHEMBL9202659 | 0.93 | PGR (0.56) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9210569 | 0.91 | PGR (0.57) | PGRRORARORCRORBPDE4A | |
| Hydrochloric Acid SCHEMBL9214838 | 0.90 | PGR (0.56) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9197407 | 0.88 | PDE4A (0.60) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9200048 | 0.88 | PGR (0.51) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9197545 | 0.88 | PDE4A (0.70) | PGRRORARORCRORBPDE4A | |
| SCHEMBL9208110 | 0.87 | PGR (0.58) | PGRRORARORCRORBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411394-B1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO KK (JP) | 1995-04-05 | — | — | EP | claimed |
| US-5010084-A | Antihistamines; asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | claimed |
| EP-0411394-A1 | Imidazoquinolone derivates | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-06 | — | — | EP | claimed |