SCHEMBL9197751

SCHEMBL9197751

CNC1c2cc(C#N)ccc2OC(C)(C)C1O

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 9/20 0.68
ABCB1 P08183 10/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197759 1.00 ABCC9 (0.68) ABCC9ABCB1
SCHEMBL9197746 1.00 ABCC9 (0.68) ABCC9ABCB1
SCHEMBL10866418 0.85 ABCB1 (0.73) ABCC9ABCB1
SCHEMBL10644302 0.85 ABCB1 (0.75) ABCC9ABCB1
SCHEMBL9273381 0.85 ABCC9 (0.78) ABCC9ABCB1
SCHEMBL9532337 0.85 ABCC9 (0.78) ABCC9ABCB1
SCHEMBL10644307 0.85 ABCB1 (0.75) ABCC9ABCB1
SCHEMBL8839473 0.85 ABCB1 (0.73) ABCC9ABCB1
SCHEMBL9532318 0.85 ABCC9 (0.78) ABCC9ABCB1
SCHEMBL9273375 0.85 ABCC9 (0.78) ABCC9ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389861-B1 Benzopyran derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1995-08-23 EP disclosed
EP-0412531-B1 Benzopyran compounds, processes for their production and pharmaceutical compositions KAKEN PHARMA CO LTD (JP) 1994-05-11 EP disclosed
US-5140031-A Pyranyl cyanoguanidine derivatives E. R. SQUIBB & SONS, INC. (US) 1992-08-18 US disclosed
US-5104890-A Potassium channel activtors; vasodilators FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1992-04-14 US disclosed
US-5095016-A Hypotensive KAKEN PHARMACEUTICAL CO., LTD. (JP) 1992-03-10 US disclosed
EP-0412531-A1 Benzopyran compounds, processes for their production and pharmaceutical compositions Kaken Pharmaceutical Co., Ltd. (JP) 1991-02-13 EP disclosed
EP-0389861-A1 Benzopyran derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-10-03 EP disclosed