Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866193 | 0.81 | DRD2 (0.74) | DRD2HTR1ADRD4HTR2A | |
| SCHEMBL10788382 | 0.81 | DRD2 (0.74) | DRD2HTR1ADRD4HTR2A | |
| SCHEMBL9589567 | 0.81 | DRD2 (0.67) | DRD2HTR1ADRD4 | |
| SCHEMBL9588981 | 0.80 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL10836726 | 0.80 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10836159 | 0.80 | DRD2 (0.74) | DRD2HTR1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL6860521 | 0.79 | DRD2 (0.73) | DRD2HTR1ADRD4HTR2A | |
| SCHEMBL9600546 | 0.79 | DRD2 (0.68) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10836083 | 0.79 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL7666898 | 0.78 | DRD2 (0.67) | DRD2HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673375-A1 | FUSED BENZO COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013659-A1 | FUSED BENZO COMPOUNDS | H. LUNDBECK A/S (DK) | 1994-06-23 | — | — | WO | disclosed |