Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203461 | 0.89 | MAPK1 (0.55) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9198223 | 0.89 | MAPK1 (0.55) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL29456993 | 0.89 | MAPK1 (0.55) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9203357 | 0.83 | MAPK1 (0.63) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9203559 | 0.82 | RAB9A (0.51) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL29631618 | 0.81 | MAPK1 (0.44) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9196919 | 0.79 | MAPK1 (0.58) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9201567 | 0.79 | MAPK1 (0.49) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9199898 | 0.77 | MAPK1 (0.55) | MAPK1HSD17B10RAB9ANPC1TDP1 | |
| SCHEMBL9206336 | 0.76 | MAPK1 (0.64) | MAPK1HSD17B10RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |