Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 18/20 | 0.74 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.67 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21601056 | 0.85 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL30023564 | 0.80 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL21601086 | 0.80 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL21601169 | 0.80 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL21601164 | 0.80 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL21601048 | 0.78 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL28941925 | 0.78 | SIRT1 (0.69) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL21599135 | 0.77 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL30022736 | 0.77 | SIRT1 (1.00) | SIRT1SIRT2SIRT5KMT2A | |
| SCHEMBL9197946 | 0.76 | KMT2A (1.00) | SIRT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578849-B1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1995-05-17 | — | — | EP | disclosed |
| EP-0578849-A1 | Process for the preparation of 1,3-dioxane-4,6-dione derivates | BIOGAL GYOGYSZERGYAR (HU) | 1994-01-19 | — | — | EP | disclosed |