SCHEMBL91980

SCHEMBL91980

FCc1c(F)cc(Br)cc1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
GPR17 Q13304 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601770 0.78 DGAT1 (0.31) DGAT1TAAR1GPR17
SCHEMBL856734 0.76 TAAR1 (0.39) DGAT1TAAR1GPR17
SCHEMBL146843 0.76 DGAT1 (0.30) DGAT1TAAR1GPR17
SCHEMBL8729481 0.76 DGAT1 (0.30) DGAT1TAAR1GPR17
SCHEMBL378361 0.76 TAAR1 (0.34) DGAT1TAAR1GPR17
SCHEMBL12332446 0.76 TAAR1 (0.31) DGAT1TAAR1GPR17
SCHEMBL21199389 0.74 CA1 (0.36) DGAT1GPR17
SCHEMBL20722814 0.74
Hydrochloric Acid SCHEMBL21715060 0.74 TAAR1 (0.38) DGAT1TAAR1
SCHEMBL3980087 0.74 TAAR1 (0.60) DGAT1TAAR1GPR17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed