Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198085 | 0.89 | SMN1; SMN2 (0.67) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6362857 | 0.86 | LMNA (0.52) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9198195 | 0.83 | LMNA (0.49) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8929781 | 0.80 | HPGD (0.58) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9202516 | 0.80 | MAPT (0.52) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6362855 | 0.79 | LMNA (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9203140 | 0.79 | LMNA (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL29450678 | 0.79 | LMNA (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8930039 | 0.79 | DHODH (0.56) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9201876 | 0.78 | LMNA (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |