Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | PGR | P06401 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | TNF | P01375 | 1/20 | 0.66 |
| ▸ | IL6 | P05231 | 1/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | GLUL | P15104 | 1/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198289 | 1.00 | NR3C1 (0.66) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL9201303 | 0.99 | NR3C1 (0.65) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL9201297 | 0.99 | NR3C1 (0.65) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL12398271 | 0.92 | NR3C1 (0.65) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL9198242 | 0.91 | NR3C1 (0.64) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| SCHEMBL9198249 | 0.91 | NR3C1 (0.64) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL9207892 | 0.91 | NR3C1 (0.64) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL9202143 | 0.91 | NR3C1 (0.64) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Mazipredone SCHEMBL25720 | 0.88 | NR3C1 (0.75) | NR3C1HIF1APGRHSD17B10CYP3A4 | |
| Mazipredone SCHEMBL3049961 | 0.88 | NR3C1 (0.75) | NR3C1HIF1APGRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238545-B1 | C20 THROUGH C26 AMINO STEROIDS | UPJOHN CO (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0263213-B1 | C20 Through C26 amino steroids | UPJOHN CO (US) | 1995-09-06 | — | — | EP | claimed |