Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 4/20 | 0.48 |
| ▸ | ATP4B | P51164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19044207 | 0.78 | MAPK1 (0.44) | LTA4HMAPK14ATP4AATP4BMAPK1 | |
| SCHEMBL29548257 | 0.78 | BRD4 (0.43) | LTA4HMAPK14ATP4AATP4BMAPK1 | |
| SCHEMBL7013077 | 0.76 | MAPT (0.52) | LTA4HMAPK14ATP4AATP4BMAPK1 | |
| SCHEMBL2354806 | 0.76 | PTGER1 (0.42) | LTA4HMAPK14CYP1A2 | |
| SCHEMBL16863408 | 0.76 | MAOB (0.47) | MAPK1FNTAFNTBPGGT1B | |
| SCHEMBL1931637 | 0.75 | MAPK1 (0.44) | LTA4HMAPK14ATP4AATP4BMAPK1 | |
| SCHEMBL31636528 | 0.75 | MAPK14 (0.46) | LTA4HMAPK14MAPK1MAPTTDP1 | |
| SCHEMBL11106437 | 0.74 | MAPK14 (0.45) | LTA4HMAPK14ATP4AATP4BMAPK1 | |
| SCHEMBL16863374 | 0.73 | KDM5A (0.50) | MEN1KMT2A | |
| SCHEMBL339812 | 0.72 | MAPT (0.71) | LTA4HMAPK14MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467637-B1 | Pyrazolo(1,5-a)pyridine compounds, and production and use thereof | SENJU PHARMA CO (JP) | 1995-10-18 | — | — | EP | claimed |