SCHEMBL339812

SCHEMBL339812

c1ccc(COc2ccccc2OCc2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.71
MAPK1 P28482 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
HTR1A P08908 4/20 0.65
DRD2 P14416 1/20 0.65
LIPE Q05469 1/20 0.63
LTA4H P09960 1/20 0.61
MAPK14 Q16539 1/20 0.61
ADRA1D P25100 3/20 0.60
ADRA1A P35348 3/20 0.60
ADRA1B P35368 3/20 0.60
ALPG P10696 1/20 0.59
PTK2B Q14289 1/20 0.59
TSHR P16473 1/20 0.57
CCNB2 O95067 1/20 0.57
CDK1 P06493 1/20 0.57
CDK4 P11802 1/20 0.57
CCNB1 P14635 1/20 0.57
CCND1 P24385 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL27831678 0.93 MAPT (0.63) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL5538708 0.93 MAPT (0.63) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL791853 0.89 HTR1A (0.74) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL27286576 0.89 MAPT (0.59) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL13434101 0.89 HTR1A (0.74) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL28457205 0.89 MAPT (0.59) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL2093962 0.89 MAPT (0.59) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL30416387 0.89 HTR1A (0.74) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL26013299 0.87 MAPT (0.63) MAPTMAPK1TDP1L3MBTL1HTR1A
SCHEMBL8216313 0.87 MAPT (0.69) MAPTMAPK1TDP1L3MBTL1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964814-A Ziegler-Natta solid catalyst component, catalyst and application thereof 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-117964812-A Alkoxy magnesium particles, and corresponding catalyst solid component and catalyst system thereof 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-117964813-A Solid catalyst component and catalyst system for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-106146394-B Hydroxytyrosol nicotinate and its preparation method and application 西安交通大学 2018-12-07 CN claimed
CN-106146394-A 3,4 dihydroxyphenyl ethanol nicotinates and its preparation method and application 西安交通大学 2016-11-23 CN claimed
CN-104177323-A Synthesis method of single enantiomer (+/-)-3-methyl-7,8-dihydroxy-isochroman-4-one UNIV CHINA PHARMA 2014-12-03 CN claimed
CN-102976957-A Method for preparing 4-amino catechol UNIV SICHUAN 2013-03-20 CN claimed
CN-101580460-B Synthetic method of 3, 4-dihydroxy phenethyl alcohol TAIZHOU ZHIQING CHEMICAL CO LTD 2012-05-23 CN claimed
CN-102093381-A 6H-benzofuran[3,2-c][1]benzopryan-6-ketone compound as well as preparation method and application of 6H-benzofuran[3,2-c][1] benzopryan-6-ketone compound UNIV SHANGHAI JIAOTONG 2011-06-15 CN claimed
CN-101235039-B Chemical total synthesis method for wedelolactone UNIV SHANGHAI JIAOTONG 2010-11-03 CN claimed
CN-101580460-A Synthesis method of 3, 4-dihydroxy phenylethanol TAIZHOU ZHIQING CHEMICAL CO LT (CN) 2009-11-18 CN claimed
CN-101235039-A Chemical total synthesis method for wedelolactone UNIV SHANGHAI JIAOTONG (CN) 2008-08-06 CN claimed
US-20250066515-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-27 US disclosed
US-12234312-B2 Solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-25 US disclosed
CN-119431212-A Synthesis method of 7-bromo-5, 6-bis (benzyloxy) benzopyrrole and derivative dimer thereof 中国科学院生物物理研究所 2025-02-14 CN disclosed
US-12173107-B2 Solid catalyst component for olefin polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-12-24 US disclosed
US-4910198-A Antiarrhythmia agent ORTHO PHARMACEUTICAL CORPORATION (US) 1990-03-20 US disclosed
US-4855426-A Process of preparing 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins ORTHO PHARMACEUTICAL CORPORATION (US) 1989-08-08 US disclosed
US-4761413-A CYTOPROTECTION, ANTISECRETORY AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-08-02 US disclosed
US-4118507-A Benzodioxincarboxamide lipogenesis inhibitors SHELL OIL COMPANY (US) 1978-10-03 US disclosed