SCHEMBL919922

SCHEMBL919922

C=C(C)C(=O)OCCCCO[Si](C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
THRB P10828 1/20 0.48
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 4/20 0.42
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.31
HCAR2 Q8TDS4 2/20 0.31
NAAA Q02083 1/20 0.31
RAD52 P43351 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29172991 0.98 TSHR (0.65) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1046104 0.96 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11804129 0.91 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL679847 0.88 THRB (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5144090 0.85 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25426 0.85 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27850647 0.85 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL81666 0.84 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22023212 0.83 TSHR (0.83) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22554429 0.83 TSHR (0.83) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110003130-A1 ORGANIC-INORGANIC HYBRID MATERIAL, OPTICAL THIN LAYER OF THIS MATERIAL, OPTICAL MATERIAL COMPRISING SAME, AND PROCESS FOR PRODUCING SAME COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-01-06 US claimed
CN-117199251-A Battery material, negative electrode, battery and battery preparation method 星欧光学股份有限公司 2023-12-08 CN disclosed
CN-104203570-B Transparent overlay body and its manufacture method 马自达汽车株式会社 2017-08-25 CN disclosed
CN-104203570-A Transparent layered object and process for producing same MAZDA MOTOR 2014-12-10 CN disclosed
EP-1137727-B1 AQUEOUS COATING COMPOSITIONS DU PONT (US) 2008-01-09 EP disclosed
EP-1174466-B1 FLAME RETARDANT, PROCESS FOR PRODUCING THE SAME, AND FLAME-RETARDANT RESIN COMPOSITION CONTAINING THE SAME MITSUBISHI RAYON CO (JP) 2006-11-02 EP disclosed
EP-1619225-A2 Aqueous pigment dispersion E.I.Du pont de nemours and company (US) 2006-01-25 EP disclosed
EP-1240255-B1 PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT DU PONT (US) 2004-09-22 EP disclosed
EP-0996689-B1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT DU PONT (US) 2002-12-18 EP disclosed
EP-1240255-A2 PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-09-18 EP disclosed
EP-1137727-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-04 EP disclosed
WO-2001025357-A2 PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-04-12 WO disclosed
US-6204319-B1 AB BLOCK COPOLYMER PIGMENT DISPERSANT RESIN OF AN A BLOCK OF A HYDROPHOBIC POLYMER HAVING AMINE GROUPS; AND A B BLOCK OF A HYDROPHILIC POLYMER HAVING HYDROXYL GROUPS AND CARBOXYL GROUPS E.I. DU PONT DE NEMOURS AND COMPANY 2001-03-20 US disclosed
US-6187854-B1 WEATHERPROOF COATINGS E. I. DU PONT DE NEMOURS AND COMPANY 2001-02-13 US disclosed
WO-2000026308-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-11 WO disclosed
EP-0996689-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-03 EP disclosed
WO-1999003938-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-28 WO disclosed
US-5859113-A COATINGS; POLYMER A SEGMENT CONSISTS OF POLYMERIZED GLYCIDYL (METH)ACRYLATE REACTED WITH AN ACID; POLYMER B SEGMENT CONTAINS REACTIVE HYDROXY ALKYL (METH)ACRYLATE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
US-5658988-A ONE-PACKAGE; AUTOMOBILE FINISHES KANSAI PAINT CO., LTD. (JP) 1997-08-19 US disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed