Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201135 | 1.00 | ELANE (0.47) | ELANEMAPTKDM4EMEN1NPC1 | |
| SCHEMBL6177695 | 0.92 | CYP2C9 (0.38) | ELANEMAPTMEN1KMT2AALOX15 | |
| SCHEMBL6173304 | 0.90 | HTR2B (0.43) | ELANENPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL9197301 | 0.88 | ELANE (0.34) | ELANEMAPTMEN1KMT2A | |
| SCHEMBL6175617 | 0.88 | ELANE (0.33) | ELANEMAPTRAB9A | |
| SCHEMBL6174860 | 0.88 | ELANE (0.33) | ELANEMAPT | |
| SCHEMBL6174391 | 0.88 | HTR2B (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9194038 | 0.87 | CYP2C9 (0.38) | ELANEMAPT | |
| SCHEMBL9193220 | 0.87 | MAPT (0.40) | MAPTHPGDALOX15 | |
| SCHEMBL6175129 | 0.87 | ELANE (0.33) | ELANEMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |