Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.32 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175129 | 0.97 | ELANE (0.33) | ELANEMAPTMEN1KMT2AHCAR2 | |
| SCHEMBL9198707 | 0.95 | CEL (0.41) | MEN1KMT2ACELGPR84CYSLTR2 | |
| SCHEMBL6174784 | 0.92 | MEN1 (0.35) | MEN1KMT2AGPR84CYP2C9VKORC1 | |
| SCHEMBL6173632 | 0.92 | CEL (0.40) | MEN1KMT2ACELGPR84CYSLTR2 | |
| SCHEMBL9198902 | 0.90 | PPARG (0.32) | ELANEMAPT | |
| SCHEMBL9199733 | 0.89 | ELANE (0.33) | ELANEMAPTHTR2BCYP2C9VKORC1 | |
| SCHEMBL9198549 | 0.89 | MEN1 (0.34) | ELANEMAPTMEN1KMT2ACEL | |
| SCHEMBL9196131 | 0.89 | MEN1 (0.34) | ELANEMAPTMEN1KMT2ACEL | |
| SCHEMBL6173304 | 0.89 | HTR2B (0.43) | ELANEGPR84HTR2B | |
| SCHEMBL9201135 | 0.88 | ELANE (0.47) | ELANEMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |