SCHEMBL9199481

SCHEMBL9199481

CC(F)CCN1CCN(CCN2CCN(c3cccc4c3OCCO4)CC2)C1=O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8307268 0.86
SCHEMBL8151415 0.85 HTR1A (0.54) HTR1A
SCHEMBL8151333 0.81 HTR1A (0.54) HTR1A
SCHEMBL8150191 0.80 HTR1A (0.61) HTR1A
SCHEMBL8150800 0.79 HTR1A (0.57) HTR1A
SCHEMBL8156696 0.78
SCHEMBL8151673 0.77
SCHEMBL8148214 0.76 HTR1A (0.52) HTR1A
SCHEMBL8156077 0.76 HTR1A (0.67) HTR1A
SCHEMBL8143460 0.73 HTR1A (0.61) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673375-A1 FUSED BENZO COMPOUNDS H. LUNDBECK A/S (DK) 1995-09-27 EP disclosed
WO-1994013659-A1 FUSED BENZO COMPOUNDS H. LUNDBECK A/S (DK) 1994-06-23 WO disclosed