Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA7 | P43166 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949585 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL2897245 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL11628696 | 0.81 | KDM4E (0.75) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL4763787 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL23574396 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL8949035 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL9205892 | 0.80 | GUSB (0.51) | — | |
| SCHEMBL11630603 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL4376727 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL9204608 | 0.79 | GUSB (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341948-B1 | Cephalosporins, process for their preparation and pharmaceutical compositions | ICI PLC (GB) | 1995-01-11 | — | — | EP | disclosed |
| US-5149803-A | Intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-09-22 | — | — | US | disclosed |
| US-5055462-A | CEPHALOSPORIN COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0341948-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |