Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949752 | 0.98 | HSP90AA1 (1.00) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8949737 | 0.95 | HSP90AA1 (0.95) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL21625862 | 0.82 | HSP90AA1 (0.73) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL608389 | 0.80 | ALDH1A1 (1.00) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL429907 | 0.76 | ALDH1A1 (0.67) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15402110 | 0.76 | ALDH1A1 (0.67) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12808728 | 0.73 | ALDH1A1 (0.61) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2553666 | 0.71 | ALDH1A1 (0.64) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9133892 | 0.70 | ALDH1A1 (0.58) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14696825 | 0.70 | MAPT (0.57) | HSP90AA1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498636-B1 | Cosmetic composition | ZENECA LTD (GB) | 1995-09-06 | — | — | EP | claimed |
| WO-1992013520-A1 | COMPOSITION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-20 | — | — | WO | claimed |
| EP-0498636-A1 | Cosmetic composition | ZENECA LIMITED (GB) | 1992-08-12 | — | — | EP | claimed |