Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195684 | 0.93 | EDNRA (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL8971991 | 0.91 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL9854234 | 0.89 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9198004 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL8972530 | 0.88 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8972525 | 0.88 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL8393351 | 0.88 | AGTR1 (0.70) | AGTR1AGTR2PPARG | |
| SCHEMBL9845754 | 0.87 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9192880 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8971427 | 0.85 | PPARG (0.52) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425921-B1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5250554-A | Cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0425921-A1 | Benzimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-05-08 | — | — | EP | disclosed |