Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174263 | 0.81 | CYP2C9 (0.46) | MEN1KMT2A | |
| SCHEMBL9199293 | 0.79 | HTR2B (0.43) | CNR1CNR2HTR2BPGAM1SMN1; SMN2 | |
| SCHEMBL9199802 | 0.78 | HTR2B (0.41) | PDE4DRAB9AMEN1KMT2AHTR2B | |
| SCHEMBL6174251 | 0.77 | CYP2C9 (0.38) | — | |
| SCHEMBL9198756 | 0.76 | HTR2B (0.43) | CNR1CNR2HTR2BPGAM1HTR2C | |
| SCHEMBL9196600 | 0.74 | HTR2B (0.46) | HTR2BPGAM1SMN1; SMN2HTR2C | |
| SCHEMBL9201597 | 0.74 | PDE4D (0.33) | PDE4DRAB9AMEN1KMT2APDE4A | |
| SCHEMBL7439058 | 0.74 | MEN1 (0.34) | RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7440421 | 0.74 | CYP2C9 (0.31) | — | |
| SCHEMBL6176061 | 0.72 | CYP2C9 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |