Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199296 | 0.82 | HTR2B (0.56) | HTR2BHTR2CPGAM1IGF1RALOX15 | |
| SCHEMBL9195193 | 0.82 | HTR2B (0.45) | HTR2BMEN1KMT2ARAB9AHTR2C | |
| SCHEMBL6178657 | 0.81 | HTR2B (0.57) | HTR2BHTR2CPGAM1IGF1RALOX15 | |
| SCHEMBL9196131 | 0.78 | MEN1 (0.34) | MEN1KMT2ARAB9A | |
| SCHEMBL9199797 | 0.78 | CNR1 (0.36) | HTR2BMEN1KMT2ARAB9AHTR2C | |
| SCHEMBL9198549 | 0.78 | MEN1 (0.34) | MEN1KMT2ARAB9A | |
| SCHEMBL6177760 | 0.78 | HTR2B (0.52) | HTR2BHTR2CPGAM1IGF1RALOX15 | |
| SCHEMBL6173771 | 0.77 | CNR1 (0.50) | HTR2BHTR2C | |
| SCHEMBL6174221 | 0.74 | HTR2B (0.49) | HTR2BRAB9AHTR2CPGAM1IGF1R | |
| SCHEMBL6176274 | 0.74 | IDH1 (0.49) | HTR2BHTR2CPGAM1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | claimed |