SCHEMBL9199830

SCHEMBL9199830

CSc1nc(N)nc(OC(F)(F)Cl)n1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 2/20 0.46
HSP90AA1 P07900 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199934 0.85 HSP90AB1 (0.48) HSP90AB1HSP90AA1
SCHEMBL7798089 0.82
SCHEMBL9185349 0.82
SCHEMBL9202407 0.81 HSP90AA1 (0.50) HSP90AA1
SCHEMBL7798118 0.78 TP53 (0.34)
SCHEMBL9190497 0.76 HSP90AA1 (0.41) HSP90AA1
SCHEMBL7805850 0.76
SCHEMBL7804018 0.75 ALDH1A1 (0.35)
SCHEMBL9185483 0.74 TSHR (0.35)
SCHEMBL7808647 0.74 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469460-B1 Herbicidal sulphonylureas, method for their preparation and intermediates BASF AG (DE) 1995-10-18 EP disclosed
US-5188657-A Herbicides consisting of sulfonyl-1,3,5-triazin-2-ylureas BASF AKTIENGESELLSCHAFT (DE) 1993-02-23 US disclosed
EP-0469460-A1 Herbicidal sulphonylureas, method for their preparation and intermediates BASF Aktiengesellschaft (DE) 1992-02-05 EP disclosed