Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206612 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EMAPTALDH1A1HTT | |
| SCHEMBL9206758 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EMAPTALDH1A1HTT | |
| SCHEMBL11148552 | 0.83 | PI4KB (0.53) | SMN1; SMN2KDM4EMAPTPI4KBALDH1A1 | |
| SCHEMBL9276931 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EMAPTPI4KBALDH1A1 | |
| SCHEMBL9506024 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EALDH1A1LMNAHTT | |
| SCHEMBL10828309 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EPI4KBALDH1A1LMNA | |
| SCHEMBL10828311 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| SCHEMBL9074842 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL11013912 | 0.74 | S1PR1 (0.42) | SMN1; SMN2KDM4E | |
| SCHEMBL4880923 | 0.74 | PI4KB (0.53) | SMN1; SMN2KDM4EPI4KBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656891-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-06-14 | — | — | EP | claimed |
| EP-0656891-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-06-14 | — | — | EP | disclosed |