Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202310 | 0.88 | MEN1 (0.71) | KMT2AMEN1PGRSRCTP53 | |
| SCHEMBL9285175 | 0.82 | MCL1 (0.41) | KMT2AMEN1PGRSRCHIF1A | |
| SCHEMBL9201791 | 0.80 | KMT2A (0.54) | KMT2AMEN1PGRSRCTP53 | |
| SCHEMBL9200254 | 0.80 | MEN1 (0.53) | KMT2AMEN1PGRSRCALDH1A1 | |
| SCHEMBL9276340 | 0.79 | MEN1 (0.53) | KMT2AMEN1PGRSRCALDH1A1 | |
| SCHEMBL9712311 | 0.79 | MEN1 (0.58) | KMT2AMEN1PGRSRCTP53 | |
| SCHEMBL9287479 | 0.79 | MEN1 (0.58) | KMT2AMEN1PGRSRCHIF1A | |
| SCHEMBL9194924 | 0.79 | MEN1 (0.58) | KMT2AMEN1PGRSRCTP53 | |
| SCHEMBL9287103 | 0.79 | MEN1 (0.57) | KMT2AMEN1PGRSRCHIF1A | |
| SCHEMBL9288974 | 0.78 | MEN1 (0.57) | KMT2AMEN1PGRSRCTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | claimed |
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |