Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197584 | 0.85 | ALDH1A1 (0.47) | MCL1KDM4EALDH1A1HIF1AMEN1 | |
| SCHEMBL9712308 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL9200461 | 0.82 | KMT2A (0.54) | DHODHKDM4EEGFRALDH1A1HPGD | |
| SCHEMBL9712333 | 0.75 | ALDH1A1 (0.49) | KDM4EEGFRALDH1A1MAPTHSD17B10 | |
| SCHEMBL15154503 | 0.72 | MEN1 (0.59) | KDM4EEGFRALDH1A1MAPTHPGD | |
| SCHEMBL9287103 | 0.71 | MEN1 (0.57) | KDM4EEGFRALDH1A1HIF1ASRC | |
| SCHEMBL9202310 | 0.71 | MEN1 (0.71) | KDM4EEGFRALDH1A1HIF1ASRC | |
| SCHEMBL9273846 | 0.71 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9201791 | 0.70 | KMT2A (0.54) | KDM4EALDH1A1HPGDHIF1ASRC | |
| SCHEMBL21375760 | 0.70 | FGFR1 (0.42) | MCL1KDM4EAKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |