Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200462 | 0.93 | HTT (0.61) | HTTMAPTLMNAPOLBHPGD | |
| SCHEMBL9208183 | 0.85 | HTT (0.51) | HTTMAPTLMNAPOLBHPGD | |
| SCHEMBL9199991 | 0.82 | HTT (0.54) | HTTMAPTLMNAPOLBHPGD | |
| SCHEMBL9210017 | 0.80 | SMN1; SMN2 (0.56) | HTTMAPTLMNAPOLBHPGD | |
| SCHEMBL9203467 | 0.79 | HTT (0.46) | HTTMAPTPOLBHPGDALDH1A1 | |
| SCHEMBL9209144 | 0.78 | POLB (0.54) | HTTMAPTPOLBHPGDCYP1A2 | |
| SCHEMBL9203585 | 0.77 | SMN1; SMN2 (0.49) | HTTMAPTPOLBHPGDALDH1A1 | |
| SCHEMBL9205844 | 0.77 | HTT (0.49) | HTTMAPTLMNAHPGDALDH1A1 | |
| SCHEMBL9200259 | 0.77 | HTT (0.49) | HTTMAPTLMNAHPGDALDH1A1 | |
| SCHEMBL9205320 | 0.77 | HTT (0.49) | HTTMAPTLMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390739-B1 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA GEIGY AG (CH) | 1995-08-09 | — | — | EP | disclosed |
| US-5155152-A | SUBSTITUTE AMINOPYRROLES AS STABILIZERS FOR CHLORINE-CONTAINING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0390739-A2 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA-GEIGY AG (CH) | 1990-10-03 | — | — | EP | disclosed |