Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 11/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210017 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2ATDP1RAB9ANPC1 | |
| SCHEMBL9200462 | 0.84 | HTT (0.61) | SMN1; SMN2KMT2ATDP1RAB9AMAPT | |
| SCHEMBL9202058 | 0.82 | HTT (0.44) | SMN1; SMN2KMT2ATDP1RAB9ANPC1 | |
| SCHEMBL9209144 | 0.80 | POLB (0.54) | SMN1; SMN2KMT2ATDP1RAB9ANPC1 | |
| SCHEMBL9203467 | 0.80 | HTT (0.46) | SMN1; SMN2KMT2ATDP1RAB9ANPC1 | |
| SCHEMBL22534127 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL11169340 | 0.78 | HTT (0.68) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL9200628 | 0.77 | HTT (0.54) | SMN1; SMN2KMT2ARAB9ANPC1MAPT | |
| SCHEMBL4495483 | 0.77 | SMN1; SMN2 (0.71) | SMN1; SMN2KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL9202782 | 0.77 | RAB9A (0.54) | SMN1; SMN2KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390739-B1 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA GEIGY AG (CH) | 1995-08-09 | — | — | EP | disclosed |
| US-5155152-A | SUBSTITUTE AMINOPYRROLES AS STABILIZERS FOR CHLORINE-CONTAINING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0390739-A2 | Substituted aminopyrroles as stabilisers in chlorinated polymers | CIBA-GEIGY AG (CH) | 1990-10-03 | — | — | EP | disclosed |