Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298000 | 1.00 | CYP1A2 (0.73) | CYP1A2AKR1C3AKR1C1NPC1MAPT | |
| SCHEMBL29169520 | 0.98 | CYP1A2 (0.71) | CYP1A2AKR1C3AKR1C1NPC1MAPT | |
| SCHEMBL11841447 | 0.88 | CYP1A2 (0.93) | CYP1A2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11841453 | 0.88 | CYP1A2 (0.93) | CYP1A2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11827285 | 0.84 | CYP1A2 (1.00) | CYP1A2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11827276 | 0.84 | CYP1A2 (1.00) | CYP1A2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17899503 | 0.84 | CYP1A2 (1.00) | CYP1A2NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28266341 | 0.83 | MAPT (0.61) | CYP1A2AKR1C3AKR1C1NPC1MAPT | |
| SCHEMBL28266343 | 0.83 | MAPT (0.61) | CYP1A2AKR1C3AKR1C1NPC1MAPT | |
| SCHEMBL2717308 | 0.80 | HSD11B1 (0.70) | CYP1A2AKR1C3AKR1C1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483616-B1 | Azolylmethylspiro-2.5-octanoles and fungicides containing the same | BASF AG (DE) | 1995-12-27 | — | — | EP | disclosed |
| US-5290792-A | Azolylmethylspiro(2.5)octanols and fungicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0483616-A2 | Azolylmethylspiro-2.5-octanoles and fungicides containing the same | BASF Aktiengesellschaft (DE) | 1992-05-06 | — | — | EP | disclosed |