Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196127 | 0.88 | NPC1 (0.51) | RXFP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9280066 | 0.83 | CHRM5 (0.46) | NPC1POLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9197464 | 0.82 | NPC1 (0.35) | RXFP1NPC1POLBHSD11B1HTT | |
| SCHEMBL9196117 | 0.80 | NPC1 (0.49) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9198807 | 0.80 | CHRM5 (0.47) | NPC1POLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9197570 | 0.80 | PARP1 (0.43) | NPC1POLBHTTSMN1; SMN2KMT2A | |
| SCHEMBL9199731 | 0.80 | NPC1 (0.40) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9200274 | 0.78 | POLB (0.42) | NPC1POLBHTTSMN1; SMN2MEN1 | |
| SCHEMBL9203731 | 0.77 | HTT (0.47) | NPC1POLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL9200337 | 0.77 | NPSR1 (0.49) | NPC1POLBHSD11B1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575425-B1 | USE OF OXAZOLO- 2,3-a]ISOINDOLE AND IMIDAZO 2,1-a]ISOINDOLE DERIVATIVES AS ANTIVIRAL DRUGS, AND NEW OXAZOLO 2,3-a]ISOINDOLE DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-11 | — | — | EP | disclosed |