Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416335 | 0.81 | SMN1; SMN2 (0.43) | TP53LMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9192786 | 0.76 | LMNA (0.43) | TP53LMNAMAPK1TSHRL3MBTL1 | |
| SCHEMBL9571823 | 0.74 | TP53 (0.42) | TP53LMNAMAPK1TSHRL3MBTL1 | |
| SCHEMBL9195078 | 0.72 | LMNA (0.50) | TP53LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL9479805 | 0.72 | TP53 (0.52) | TP53LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL9817826 | 0.72 | TP53 (0.44) | TP53LMNAMAPK1TSHRL3MBTL1 | |
| SCHEMBL9197914 | 0.71 | TP53 (0.49) | TP53LMNAMAPK1TSHRL3MBTL1 | |
| SCHEMBL9440015 | 0.70 | TP53 (0.43) | TP53LMNAMAPK1TSHRL3MBTL1 | |
| SCHEMBL9416345 | 0.67 | PIK3CG (0.36) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9481321 | 0.64 | MAPT (0.43) | TP53LMNAMAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556396-B1 | SUBSTITUTED PYRAZOLE DERIVATIVE AND AGROHORTICULTURAL BACTERICIDE | NISSAN CHEMICAL IND LTD (JP) | 1995-09-20 | — | — | EP | disclosed |
| EP-0556396-A1 | SUBSTITUTED PYRAZOLE DERIVATIVE AND AGROHORTICULTURAL BACTERICIDE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1993-08-25 | — | — | EP | disclosed |