⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19220304 | 1.00 | — | — | |
| SCHEMBL21945204 | 1.00 | — | — | |
| SCHEMBL23704527 | 0.88 | LRRK2 (0.31) | — | |
| SCHEMBL26780073 | 0.78 | ADRA1A (0.30) | — | |
| SCHEMBL25515636 | 0.78 | ADRA1A (0.30) | — | |
| SCHEMBL15807962 | 0.75 | — | — | |
| SCHEMBL30892164 | 0.75 | — | — | |
| SCHEMBL29215649 | 0.75 | — | — | |
| SCHEMBL24146813 | 0.75 | — | — | |
| SCHEMBL17145125 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058708-A | Alkynyl alcohol derivative and medical application thereof | 中国药科大学 | 2025-05-30 | — | — | CN | claimed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| US-20250207171-A1 | KETOREDUCTASE POLYPEPTIDES AND POLYNUCLEOTIDES | CODEXIS INC (RE) | 2025-06-26 | — | — | US | disclosed |
| CN-120058708-A | Alkynyl alcohol derivative and medical application thereof | 中国药科大学 | 2025-05-30 | — | — | CN | disclosed |
| US-12252723-B2 | Ketoreductase polypeptides and polynucleotides | CODEXIS, INC. (US) | 2025-03-18 | — | — | US | disclosed |
| CN-119613408-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-110914271-B | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-12-10 | — | — | CN | disclosed |
| EP-4467199-A2 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2024-11-27 | — | — | EP | disclosed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-20240335443-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
| WO-2012123522-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | disclosed |
| US-20120214762-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | GENENTECH, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214762-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | GENENTECH, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214762-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | GENENTECH, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| EP-0563286-A4 | NOVEL CSAIDS | SMITHKLINE BEECHAM CORP (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0565582-A4 | NOVEL CSAIDS. | SMITHKLINE BEECHAM CORP (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0565582-A1 | NOVEL CSAIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0563286-A1 | NOVEL CSAIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992010190-A1 | NOVEL CSAIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992010498-A1 | NOVEL CSAIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |