Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068953 | 0.73 | TSHR (0.35) | TSHR | |
| SCHEMBL7001560 | 0.73 | TSHR (0.35) | TSHRL3MBTL1HPGDKDM4EMEN1 | |
| SCHEMBL10428856 | 0.68 | TSHR (0.31) | TSHR | |
| SCHEMBL816203 | 0.67 | TSHR (0.36) | TSHRL3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL16531355 | 0.66 | CYP11B1 (0.41) | TSHRL3MBTL1HPGDKDM4EMEN1 | |
| SCHEMBL5324027 | 0.65 | TSHR (0.37) | TSHRBCL2L1HPGDKDM4EMEN1 | |
| SCHEMBL3957779 | 0.64 | NPC1 (0.31) | MEN1KMT2A | |
| SCHEMBL6846099 | 0.64 | KDM4E (0.50) | L3MBTL1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8020476 | 0.62 | GRIN2D (0.32) | TSHRMEN1KMT2A | |
| SCHEMBL353175 | 0.60 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | claimed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | claimed |
| WO-2020241853-A1 | BENZOTRIAZOLE DERIVATIVE | 宇部興産株式会社 | 2020-12-03 | — | — | WO | disclosed |