Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16531355 | 0.80 | CYP11B1 (0.41) | TSHRCYP11B1CYP11B2ALDH1A1TDP1 | |
| SCHEMBL717055 | 0.71 | TDP2 (0.46) | MEN1NPC1LMNAMAPTHTT | |
| SCHEMBL10651836 | 0.70 | GALR1 (0.36) | TSHRALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL9845507 | 0.69 | CYP11B1 (0.61) | TSHRCYP11B1CYP11B2ALDH1A1TDP1 | |
| SCHEMBL2300209 | 0.67 | CYP3A4 (0.37) | TSHRTDP1CYP3A4 | |
| SCHEMBL7001560 | 0.65 | TSHR (0.35) | TSHRALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL11068953 | 0.65 | TSHR (0.35) | TSHR | |
| SCHEMBL30125264 | 0.65 | CYP11B1 (0.56) | TSHRCYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL9201217 | 0.65 | TSHR (0.35) | TSHRALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL27445644 | 0.65 | CYP11B1 (0.56) | TSHRCYP11B1CYP11B2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095383-A2 | PRODRUGS | MYRIAD GENETICS, INC. (US) | 2007-08-23 | — | — | WO | disclosed |