Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872753 | 0.93 | AKR1B1 (0.87) | AKR1B1 | |
| SCHEMBL1590287 | 0.88 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9202242 | 0.86 | AKR1B1 (0.79) | AKR1B1 | |
| SCHEMBL10430980 | 0.86 | AKR1B1 (0.75) | AKR1B1 | |
| SCHEMBL9206592 | 0.82 | AKR1B1 (0.70) | AKR1B1 | |
| SCHEMBL9322386 | 0.81 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9195294 | 0.80 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9871647 | 0.79 | AKR1B1 (0.79) | AKR1B1 | |
| SCHEMBL9871499 | 0.79 | AKR1B1 (0.65) | AKR1B1 | |
| SCHEMBL9204262 | 0.79 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401981-B1 | Pyridazinone deriratives | PFIZER (US) | 1995-04-26 | — | — | EP | disclosed |