Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590287 | 0.84 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9201252 | 0.80 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9872753 | 0.80 | AKR1B1 (0.87) | AKR1B1 | |
| SCHEMBL9322386 | 0.79 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9321335 | 0.77 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL8466444 | 0.75 | AKR1B1 (0.60) | AKR1B1 | |
| SCHEMBL9201275 | 0.75 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10584475 | 0.71 | AKR1B1 (0.67) | AKR1B1 | |
| SCHEMBL8304641 | 0.70 | AKR1B1 (0.62) | AKR1B1 | |
| SCHEMBL9323686 | 0.70 | AKR1B1 (0.79) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662962-A1 | SUBSTITUTED PYRIMIDINES FOR CONTROL OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007867-A1 | SUBSTITUTED PYRIMIDINES FOR CONTROL OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1994-04-14 | — | — | WO | disclosed |