Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199301 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9273738 | 0.86 | PTGS2 (0.72) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL25150243 | 0.86 | PTGS2 (0.72) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9208582 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL13866593 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5147701 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL14903140 | 0.85 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL4032238 | 0.85 | PTGS1 (0.74) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL9740969 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL7243347 | 0.82 | PTGS2 (0.81) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |