Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.52 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410598 | 0.86 | CYP17A1 (0.56) | CYP19A1CYP24A1CYP27B1CYP17A1 | |
| Hydrochloric Acid SCHEMBL3643107 | 0.85 | CYP17A1 (0.48) | CYP17A1CYP3A4 | |
| SCHEMBL9432260 | 0.83 | CYP19A1 (0.58) | CYP19A1CYP17A1 | |
| Hydrochloric Acid SCHEMBL3650043 | 0.82 | CYP24A1 (0.53) | CYP19A1CYP24A1CYP17A1CYP26A1 | |
| Hydrochloric Acid SCHEMBL3757776 | 0.81 | CYP19A1 (0.60) | CYP19A1CYP24A1CYP17A1CYP3A4CYP26A1 | |
| SCHEMBL19054886 | 0.77 | CYP19A1 (0.55) | CYP19A1HSD17B10CYP17A1CYP26A1 | |
| Hydrochloric Acid SCHEMBL3649216 | 0.76 | CYP19A1 (0.56) | CYP19A1CYP24A1CYP27B1CYP17A1CYP3A4 | |
| SCHEMBL8973344 | 0.76 | CYP17A1 (0.71) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL18123005 | 0.76 | CYP19A1 (0.59) | CYP19A1CYP24A1CYP17A1CYP26A1MEN1 | |
| SCHEMBL20830319 | 0.76 | CYP19A1 (0.59) | CYP19A1CYP24A1CYP17A1CYP26A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649423-A1 | PROCESS FOR PREPARING 1,3-DIOXOLANE DERIVATIVES. | SYNTEX INC (US) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993025549-A1 | PROCESS FOR PREPARING 1,3-DIOXOLANE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1993-12-23 | — | — | WO | disclosed |