Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 20/20 | 0.91 |
| ▸ | PRKCA | P17252 | 20/20 | 0.91 |
| ▸ | PRKCE | Q02156 | 19/20 | 0.91 |
| ▸ | PRKCG | P05129 | 18/20 | 0.91 |
| ▸ | PRKCH | P24723 | 18/20 | 0.91 |
| ▸ | PRKCD | Q05655 | 18/20 | 0.91 |
| ▸ | PRKACA | P17612 | 14/20 | 0.91 |
| ▸ | PRKACG | P22612 | 9/20 | 0.83 |
| ▸ | PRKACB | P22694 | 9/20 | 0.83 |
| ▸ | PRKCZ | Q05513 | 8/20 | 0.83 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.83 |
| ▸ | PRKCI | P41743 | 2/20 | 0.83 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.83 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.83 |
| ▸ | GRK2 | P25098 | 1/20 | 0.83 |
| ▸ | GRK4 | P32298 | 1/20 | 0.83 |
| ▸ | GRK5 | P34947 | 1/20 | 0.83 |
| ▸ | GRK3 | P35626 | 1/20 | 0.83 |
| ▸ | GRK6 | P43250 | 1/20 | 0.83 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Balanol SCHEMBL9198347 | 0.96 | PRKCB (0.91) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Balanol SCHEMBL9198287 | 0.96 | PRKCB (0.91) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Balanol SCHEMBL9393094 | 0.96 | PRKCB (0.91) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Trifluoroacetic Acid SCHEMBL9396433 | 0.94 | PRKCB (0.81) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Trifluoroacetic Acid SCHEMBL9196770 | 0.93 | PRKCB (0.90) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Trifluoroacetic Acid SCHEMBL9393148 | 0.93 | PRKCB (0.90) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Balanol SCHEMBL62129 | 0.91 | PRKCB (1.00) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Balanol SCHEMBL62128 | 0.91 | PRKCB (1.00) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Balanol SCHEMBL12012990 | 0.91 | PRKCB (1.00) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| Trifluoroacetic Acid SCHEMBL9201598 | 0.91 | PRKCB (0.81) | PRKCBPRKCAPRKCEPRKCGPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |