Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185693 | 0.84 | ALOX5 (0.65) | PTPN1ALDH1A1LMNAABCG2 | |
| SCHEMBL7186131 | 0.84 | ALOX5 (0.65) | PTPN1ALDH1A1LMNAABCG2 | |
| SCHEMBL9115187 | 0.83 | PTPN1 (0.60) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9115195 | 0.83 | PTPN1 (0.60) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7192296 | 0.82 | PTPN1 (0.64) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7192300 | 0.82 | PTPN1 (0.64) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7187135 | 0.82 | PTPN1 (0.70) | PTPN1ABCG2TNFRSF1ADPP4 | |
| SCHEMBL7192619 | 0.82 | PTPN1 (0.70) | PTPN1ABCG2TNFRSF1ADPP4 | |
| SCHEMBL7184798 | 0.82 | TNFRSF1A (0.74) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7177833 | 0.82 | TNFRSF1A (0.74) | PTPN1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | claimed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | claimed |