Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199967 | 0.95 | TDP1 (0.39) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9367094 | 0.94 | TDP1 (0.45) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9657484 | 0.90 | MAPT (0.36) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9366169 | 0.89 | KCNH2 (0.41) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9371576 | 0.89 | TDP1 (0.45) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9658446 | 0.88 | MAPT (0.36) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9077899 | 0.86 | TDP1 (0.42) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9077900 | 0.86 | TDP1 (0.42) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL9366452 | 0.85 | KCNH2 (0.39) | TDP1HSD17B10NR1I2ALDH1A1PGR | |
| SCHEMBL8988441 | 0.84 | NR1I2 (0.52) | TDP1HSD17B10NR1I2ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287116-B1 | Thiadiazolylacetamide cephem derivatives | EISAI CO LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-4929612-A | ANTIBIOTICS, BACTERICIDES | EISAI CO., LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| EP-0287116-A2 | Thiadiazolylacetamide cephem derivatives | Eisai Co., Ltd. (JP) | 1988-10-19 | — | — | EP | disclosed |