Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184726 | 0.94 | ABCG2 (0.57) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7190651 | 0.91 | ABCG2 (0.61) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7190280 | 0.86 | ABCG2 (0.55) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7184382 | 0.84 | LMNA (0.51) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7189298 | 0.84 | DPP4 (0.47) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7192282 | 0.83 | LMNA (0.58) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7185759 | 0.83 | ABCG2 (0.43) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7186631 | 0.83 | PTPN1 (0.59) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7185855 | 0.82 | LMNA (0.49) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7181384 | 0.82 | ABCG2 (0.53) | ABCG2CAPN1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |