Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.59 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205218 | 0.81 | MAPK1 (0.72) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9429589 | 0.80 | ADRB1 (0.75) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL8780899 | 0.79 | TAAR1 (0.67) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9428809 | 0.79 | ADRB1 (0.71) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9429159 | 0.79 | TAAR1 (0.48) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9428920 | 0.78 | SLC22A2 (0.56) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| Oxalic Acid SCHEMBL9428776 | 0.78 | TAAR1 (0.62) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9428818 | 0.78 | ADRB1 (0.64) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9429051 | 0.78 | CYP1A2 (0.51) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 | |
| SCHEMBL9428374 | 0.78 | ADRB1 (0.75) | MAPK1ADRB1SLC6A4SLC22A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430693-B1 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0430693-A2 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-05 | — | — | EP | disclosed |