SCHEMBL9201766

SCHEMBL9201766

O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)CCCN2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9199392 0.99 ACHE (0.98) ACHE
SCHEMBL9201840 0.97 ACHE (1.00) ACHE
Fumaric Acid SCHEMBL9208275 0.95 ACHE (0.91) ACHE
Fumaric Acid SCHEMBL9208284 0.95 ACHE (0.91) ACHE
SCHEMBL4512070 0.94 ACHE (1.00) ACHE
SCHEMBL9209651 0.92 ACHE (1.00) ACHE
Fumaric Acid SCHEMBL9200183 0.90 ACHE (0.91) ACHE
Fumaric Acid SCHEMBL9200177 0.90 ACHE (0.91) ACHE
Hydrochloric Acid SCHEMBL27357909 0.90 ACHE (0.81) ACHE
Zanapezil SCHEMBL29366424 0.89 ACHE (1.00) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487071-B1 Condensed heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-07-05 EP disclosed
US-5273974-A Condensed heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-12-28 US disclosed
EP-0487071-A1 Condensed heterocyclic compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1992-05-27 EP disclosed