Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209095 | 1.00 | PTGS2 (0.63) | PTGS2NR3C2PTGS1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9199123 | 0.85 | PTGS2 (0.46) | PTGS2NR3C2PTGS1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9207583 | 0.84 | PTGS2 (0.46) | PTGS2NR3C2PTGS1MEN1KMT2A | |
| SCHEMBL9207196 | 0.84 | PTGS2 (0.46) | PTGS2NR3C2PTGS1MEN1KMT2A | |
| SCHEMBL9202425 | 0.84 | PTGS2 (0.48) | PTGS2NR3C2PTGS1KDM1A | |
| SCHEMBL9210967 | 0.84 | PTGS2 (0.69) | PTGS2NR3C2PTGS1MEN1KMT2A | |
| SCHEMBL9207646 | 0.83 | PTGS2 (0.65) | PTGS2NR3C2PTGS1 | |
| SCHEMBL8641979 | 0.83 | PTGS2 (0.45) | PTGS2NR3C2PTGS1 | |
| SCHEMBL8642066 | 0.83 | PTGS2 (0.47) | PTGS2NR3C2PTGS1 | |
| SCHEMBL9207835 | 0.82 | PTGS2 (0.51) | PTGS2PTGS1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418845-B1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5134142-A | PYRAZOLE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0418845-A1 | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |