Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199980 | 0.93 | LTB4R (0.66) | LTB4RLTB4R2 | |
| SCHEMBL9199491 | 0.92 | LTB4R (0.83) | LTB4RLTB4R2 | |
| SCHEMBL9201426 | 0.92 | LTB4R (0.86) | LTB4RLTB4R2 | |
| SCHEMBL9203571 | 0.87 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL14021665 | 0.87 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9206385 | 0.86 | LTB4R (0.76) | LTB4RLTB4R2 | |
| SCHEMBL9199574 | 0.85 | LTB4R (0.83) | LTB4RLTB4R2 | |
| SCHEMBL9206284 | 0.85 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL9206279 | 0.85 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL9203661 | 0.82 | NPC1 (0.53) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538416-B1 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5232948-A | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-08-03 | — | — | US | disclosed |
| WO-1992004315-A1 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-03-19 | — | — | WO | disclosed |