Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HRH1 | P35367 | 16/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202257 | 0.91 | MEN1 (0.59) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9386499 | 0.89 | ALDH1A1 (0.58) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9205131 | 0.86 | ALDH1A1 (0.81) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9310961 | 0.86 | MEN1 (0.54) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9430824 | 0.84 | ALDH1A1 (0.63) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9383466 | 0.81 | MEN1 (0.59) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9429355 | 0.80 | MEN1 (0.58) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9429034 | 0.80 | MEN1 (0.54) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9429643 | 0.78 | MEN1 (0.55) | MEN1ALDH1A1KMT2AHRH1ADRA1D | |
| SCHEMBL9388150 | 0.77 | MEN1 (0.54) | MEN1ALDH1A1KMT2AHRH1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430693-B1 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-31 | — | — | EP | disclosed |
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0430693-A2 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |