Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tenosiprol SCHEMBL2109048 | 1.00 | DAO (0.41) | DAONPC1RAB9AMAPTKMT2A | |
| SCHEMBL9203491 | 0.82 | DAO (0.40) | DAONPC1RAB9AMAPTKMT2A | |
| SCHEMBL3448795 | 0.80 | CHRNA7 (0.55) | KMT2A | |
| SCHEMBL27897636 | 0.80 | CHRNA7 (0.55) | KMT2A | |
| SCHEMBL27897614 | 0.80 | CHRNA7 (0.55) | KMT2A | |
| SCHEMBL3448793 | 0.80 | CHRNA7 (0.55) | KMT2A | |
| Hydrochloric Acid SCHEMBL5518835 | 0.78 | CHRNA7 (0.54) | KMT2A | |
| SCHEMBL9581895 | 0.77 | CES2 (0.50) | DAONPC1RAB9AMAPTKMT2A | |
| SCHEMBL24354951 | 0.75 | CHRNA7 (0.50) | KMT2A | |
| SCHEMBL3195638 | 0.74 | TSHR (0.53) | DAONPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532506-B1 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent | PULITZER ITALIANA (IT) | 1995-10-18 | — | — | EP | claimed |
| EP-0532506-B1 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent | PULITZER ITALIANA (IT) | 1995-10-18 | — | — | EP | disclosed |
| EP-0532506-B1 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent | PULITZER ITALIANA (IT) | 1995-10-18 | — | — | EP | disclosed |
| EP-0532506-B1 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent | PULITZER ITALIANA (IT) | 1995-10-18 | — | — | EP | disclosed |
| EP-0532506-A1 | HYDROXYPROLINE DERIVATIVE, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. | PULITZER ITALIANA (IT) | 1993-03-24 | — | — | EP | disclosed |
| EP-0532506-A1 | HYDROXYPROLINE DERIVATIVE, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. | PULITZER ITALIANA (IT) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018896-A1 | HYDROXYPROLINE DERIVATIVE, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | PULITZER ITALIANA S.R.L. (IT) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991018896-A1 | HYDROXYPROLINE DERIVATIVE, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | PULITZER ITALIANA S.R.L. (IT) | 1991-12-12 | — | — | WO | disclosed |