Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728172 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL195654 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL9728220 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL9200986 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL9734477 | 0.91 | ALDH1A1 (0.39) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL20634425 | 0.89 | ALDH1A1 (0.40) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL5095110 | 0.89 | ATM (0.43) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL8541738 | 0.89 | ATM (0.43) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL9728021 | 0.89 | ATM (0.43) | ALDH1A1ATMMAPTHPGDTDP1 | |
| SCHEMBL9381292 | 0.89 | ATM (0.43) | ALDH1A1ATMMAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163371-A | Meropenem side chain optical isomer, preparation method and application thereof, and detection method of impurities in Meropenem side chain | 天津市敬业精细化工有限公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |